SECOND European Vascular Genomics Network (EVGN) Summer School
Bench-work and basic science leading to ethical perspectives
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A selected set of scientific and non-strictly scientific topics regarding cardiovascular disease (CVD) was the matter of exhaustive learning and critical discussion during the EVGN Second Summer School, that was held in Erice (Italy) from September 10th to 14th 2006. The programme, developed throughout three full days and a half, was carried out by EVGN Senior Scientists convened in Sicily from seven European countries (United Kingdom, Sweden, The Netherlands, France, Germany, Israel and, of course, Italy). Twenty focused lectures offered a hundred attendees - EVGN PhD students close to the discussion of their thesis - a wide angle perspective on who’s who and what’s what issues about: angiogenesis; the use of animal models for the investigation of the vascular system development; gene and cell therapies applied to CVD; procedural aspects of the clinical trials, just to name a few. |
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| In his lesson, for example, Paolo Madeddu from the University of Bristol focused on the mechanisms that trigger the microvascular damage in diabetic people, and presented several theories that try to explain why high glucose levels damage preferentially the endothelial cells. He also pointed out to the fact that these cells are harmless towards the glucose inflow. “In my seminar I tried to give an overview on feasible therapeutic approaches against microangiopathy, then I tried to stimulate the students to elaborate their own theories”.
Anton Horrevoets, on his part, discussed the importance of exploiting data-mining, also combined to other techniques, in the investigation of endothelial cells and their responses to inflammatory and atherosclerotic events from a genomic point of view. Special attention was devoted to ancillary, but not of less importance, topics: three lectures targeted the management of the intellectual property, patents and commercialization; the importance of communicating science to the public, and the ethical aspects stemming from some clinical applications of the modern technologies, in compliance with the current guidance expressed by the European Union, that is highly oriented towards public understanding of science and public governance. The purpose of this School, recall the organizers, is to provide the students with an all round perception of CVD and all the possible related issues. “We are working to make the current year’s School even more attractive and productive” comments Tedgui, coordinator of the EVGN. |